At Jefferson Radiation Oncology, we offer a full range of sophisticated radiation modalities for tackling brain tumors and brain metastases including intensity-modulated radiation therapy (IMRT), stereotactic fractionated radiation therapy, and stereotactic radiosurgery.

Primary brain tumors are often infiltrative and can cause headaches, nausea, visual changes, gait problems or focal neurological symptoms. Brain tumors are somewhat unique in that they do not typically travel via the lymph system and rarely metastasize (meaning, spread to other parts of the body) outside of the central nervous system.


The Glioma family of primary brain tumors - including glioblastoma multiforme (GBM), astrocytoma, oligodendroglioma, ependymoma - are commonly treated with radiation. New data shows that other medicines, usually well-tolerated biological agents such as temazolamide, are also an effective treatment option for gliomas. Glioblastoma is the most common form of primary brain cancer. Approximately 12,500 patients are diagnosed each year in the US with glioblastoma or tumors that typically progress to glioblastoma.


Benign brain tumors, though often not infiltrative or metastatic, sometimes cause local symptoms by compressing healthy brain tissue, but can often be controlled with radiation.


Brain metastases - tumor deposits from elsewhere in the body that lodge in the brain - are the most common intra-axial brain tumor. Brain metastases are a common problem for patients who are living with cancer.


Radiation therapy can cure some brain tumors and is used to improve quality of life and delay progression in other cases. Radiation therapy may be used as primary therapy or as post-operative treatment.


At Jefferson Radiation Oncology, we have special expertise and sophisticated technology for fighting brain metastases and preserving quality of life. Brain SRS can be used either in place of, or in conjunction with, fractionated external beam radiation therapy. When compared with conventional treatments, brain SRS not only offers superior tumor control, but also has fewer side effects (i.e. minimal or no hair loss, less fatigue) and requires fewer patient visits to our department. Studies have shown that brain SRS boosts survival in patients with single brain metastases by 33 percent, when added to whole brain radiation.


Optune™ is a medical device that has been shown to significantly increase survival in patients with a brain tumor known as glioblastoma multiforme (GBM). This survival increase represents an important breakthrough for patients with these types of brain tumors. The Optune device is generally well-tolerated, and our physicians will work to see if this should be part of your treatment program.

Dr. Sidd“I am proud that we offer superior treatment for these difficult tumors. We have an excellent group of neurosurgeons and oncologists. I connect patients with a surgeons who specialize in brain tumor surgery. We started offering Optune to our patients in March 2016, and patients and families have tolerated this extremely well,” says Sidd Padmanabha, M.D.

For more information, download the Optune™ Fact Sheet